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Icon tunicæ villosæ intestini duodeni

BLEULAND, J. · Trajecti ad Rhenum, B. Wild et J. Altheer, 1789
Icon tunicæ villosæ intestini duodeni — 1Icon tunicæ villosæ intestini duodeni — 2Icon tunicæ villosæ intestini duodeni — 3Icon tunicæ villosæ intestini duodeni — 4Icon tunicæ villosæ intestini duodeni — 5Icon tunicæ villosæ intestini duodeni — 6Icon tunicæ villosæ intestini duodeni — 7Icon tunicæ villosæ intestini duodeni — 8
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Icon tunicæ villosæ intestini duodeni
€3,200≈ US$ 3,600 · rate of 28 September 2026
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MedicineBookRare Books and Manuscripts
Macro-categoryRare Books and Manuscripts
SubcategoryMedicine
AuthorBLEULAND, J.
Place of printingTrajecti ad Rhenum
Publisher / MakerB. Wild et J. Altheer
Year1789

a new era for Anatomical Pathology:

The rise of coloured illustrations

First edition of Bleuland’s histological investigation of duodenal tissue

Bleuland, Jan. Icon tunicæ villosæ intestini duodeni, juxta felicem vasculorum impletionem. Ipsis coloribus, qui in præparato conspiciuntur edita. Trajecti ad Rhenum [Utrecht]: apud B. Wild et J. Altheer, 1789.

4to (21 x 19 cm), later paper wrapper, pp. 10, [2-last leaf blank missing] signature A⁴ B² (B2 blank, missing)

One coloured plate representing a sample of duodenal tissue

Jan Bleuland (1756-1838) was a renowned physician, professor of Anatomy, Physiology, Obstetrics and rector of Utrecht University.

He became famous for perfecting a technique of injecting fixatives and dyes into the soft tissues of the human body to reveal previously invisible anatomical details. The printed illustrations resulting from his technique are unique in their precision in depicting microscopic structures.

Among Bleuland's greatest achievements was his ability to visualize vascular systems, making even the smallest blood vessels perfectly visible, while preserving the true colours and textures of the tissues.

The ability to produce detailed and realistic tissue images, developed and improved by Bleuland, together with the work of his colleague, the Scottish pathologist Matthew Baillie (1761–1823), gave a significant boost to innovations in anatomical pathology.

During his distinguished career, Bleuland produced more than two thousand anatomical preparations, and his vast collection of specimens is now preserved at Utrecht Medical University.

“Bleuland focused on the soft parts [of human body], which involved a much wider spectrum of organs and diseases and posed a different set of problems to technicians in the preparation of the specimens” (Meli, p.211, op. cit.)

“During his career Bleuland published a number of illustrated anatomical works printed in color, showing a special interest in the fine structure of healthy and diseased states of the organs and tunics of the digestive tract. Bleuland made a collection of over two and a half thousand anatomical preparations, with the assistance of Petrus Koning, whom he had trained as his attendant and as a surgeon from 1800” (Meli, op.cit.)

Conditions: Small restoration at lower margins; overall a good copy.

Provenance: Ownership signature at title page

References: Domenico Bertoloni Meli, The Rise of Pathological Illustrations: Baillie, Bleuland, and Their Collections, Bulletin of the History of Medicine, Volume 89, Number 2, Summer 2015, pp. 209-242 (Article); Florian Rodari, Anatomie de la couleur, 124; James G. Mundies’s Cabinet of Curiosite’s, February 2008; Blake p. 50; not in Waller or Wellcome.